Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:activatedBy |
gptkb:cyclin_A
gptkb:cyclin_E |
| gptkbp:alternativeName |
gptkb:cell_division_protein_kinase_2
gptkb:cyclin-dependent_kinase_II gptkb:CDK2 |
| gptkbp:associatedWith |
gptkb:cancer
|
| gptkbp:biologicalProcess |
ATP binding
protein serine/threonine kinase activity |
| gptkbp:EC_number |
2.7.11.22
|
| gptkbp:encodedBy |
gptkb:CDK2_gene
|
| gptkbp:function |
regulation of cell cycle
DNA replication G1/S transition of mitotic cell cycle |
| gptkbp:gene |
gptkb:CDK2
|
| https://www.w3.org/2000/01/rdf-schema#label |
Cyclin-dependent kinase 2
|
| gptkbp:inhibitedBy |
gptkb:p21
gptkb:p27 |
| gptkbp:locatedOnChromosome |
12q13
|
| gptkbp:location |
gptkb:nucleus
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:PDB |
1FIN
|
| gptkbp:phosphorylates |
gptkb:RB1
gptkb:NPAT gptkb:p27Kip1 |
| gptkbp:relatedTo |
cell proliferation
cell cycle arrest |
| gptkbp:UniProtID |
P24941
|
| gptkbp:bfsParent |
gptkb:HGNC:1633
gptkb:CDK2 |
| gptkbp:bfsLayer |
7
|