cell division protein kinase 2
GPTKB entity
Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:CDK2
|
| gptkbp:associatedWith |
gptkb:cancer
|
| gptkbp:biologicalProcess |
DNA replication
protein serine/threonine kinase activity G1/S transition of mitotic cell cycle |
| gptkbp:cellularComponent |
gptkb:nucleus
|
| gptkbp:enzymeClassification |
EC 2.7.11.22
|
| gptkbp:foundIn |
nucleoplasm
|
| gptkbp:function |
regulation of cell cycle
|
| gptkbp:gene |
gptkb:CDK2
|
| https://www.w3.org/2000/01/rdf-schema#label |
cell division protein kinase 2
|
| gptkbp:inhibitedBy |
gptkb:p21
gptkb:p27 gptkb:roscovitine |
| gptkbp:interactsWith |
gptkb:cyclin_A
gptkb:cyclin_E |
| gptkbp:locatedOnChromosome |
12q13
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:PDB |
gptkb:1HCK
1FIN 1B39 |
| gptkbp:phosphorylates |
gptkb:NPAT
gptkb:RB1_protein |
| gptkbp:regulates |
cell proliferation
|
| gptkbp:UniProtID |
P24941
|
| gptkbp:bfsParent |
gptkb:cyclin_dependent_kinase_2
gptkb:CDK2_gene gptkb:Cyclin-dependent_kinase_2 gptkb:HGNC:1014 |
| gptkbp:bfsLayer |
8
|