Statements (53)
Predicate | Object |
---|---|
gptkbp:instance_of |
gptkb:protein
|
gptkbp:bfsLayer |
5
|
gptkbp:bfsParent |
gptkb:cyclin-dependent_kinases
|
gptkbp:application |
CD K2
|
gptkbp:damage |
ubiquitination
|
gptkbp:established |
gptkb:cyclin_D
p21 p27 |
gptkbp:has_role |
DNA replication
|
https://www.w3.org/2000/01/rdf-schema#label |
cyclin E
|
gptkbp:interacts_with |
CD K2
|
gptkbp:is_aimed_at |
anticancer drugs
|
gptkbp:is_associated_with |
gptkb:healthcare_organization
gptkb:neuroblastoma endometrial cancer |
gptkbp:is_found_in |
gptkb:physicist
|
gptkbp:is_involved_in |
apoptosis regulation
cellular homeostasis cellular metabolism chromatin remodeling cellular proliferation cellular senescence tumor suppression tumor microenvironment cellular aging cellular differentiation cellular signaling pathways tumor progression cellular repair mechanisms cellular adaptation cellular response to DNA damage cellular invasion G1 phase of cell cycle |
gptkbp:is_linked_to |
cellular stress response
tumorigenesis metastasis poor prognosis in cancers cancer metastasis |
gptkbp:is_part_of |
cyclin family
cell cycle regulatory network |
gptkbp:is_represented_in |
gptkb:healthcare_organization
gptkb:embryonic_development ovarian cancer various tissues breast tissue head and neck cancer |
gptkbp:is_studied_in |
cell biology
|
gptkbp:measures |
cancer diagnostics
|
gptkbp:regulates |
cell cycle progression
oncogenes cellular checkpoints micro RN As E2 F transcription factors |