cyclin-dependent kinase II

URI: https://gptkb.org/entity/cyclin-dependent_kinase_II
GPTKB entity
Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:enzyme
gptkbp:alternativeName gptkb:cell_division_protein_kinase_2
gptkb:CDK2
gptkbp:biologicalProcess protein serine/threonine kinase activity
gptkbp:cofactor gptkb:cyclin
gptkbp:containsGene gptkb:CDK2
gptkbp:EC_number 2.7.11.22
gptkbp:Entrez_Gene_ID ENSG00000123374
gptkbp:foundIn gptkb:Mus_musculus
gptkb:Homo_sapiens
gptkbp:function regulation of cell cycle
gptkbp:hasRefSeqID gptkb:NP_001789.2
gptkbp:HGNC_ID 1771
https://www.w3.org/2000/01/rdf-schema#label cyclin-dependent kinase II
gptkbp:inhibitedBy gptkb:p21
gptkb:p27
gptkbp:involvedIn DNA replication
G1/S transition of mitotic cell cycle
gptkbp:locatedOnChromosome 12q13
gptkbp:molecularWeight 33 kDa
gptkbp:OMIM 116940
gptkbp:partOf gptkb:cyclin-dependent_kinase_family
gptkbp:PDB gptkb:1HCK
1FIN
gptkbp:phosphorylates gptkb:Rb_protein
gptkb:histone_H1
gptkbp:regulates gptkb:cyclin_A
gptkb:cyclin_E
gptkbp:UniProtID P24941
gptkbp:bfsParent gptkb:Cyclin-dependent_kinase_2
gptkbp:bfsLayer 8