microglia

GPTKB entity

Statements (48)
Predicate Object
gptkbp:instanceOf immune response
glial cell
gptkbp:abnormalFunctionAssociatedWith gptkb:trauma
gptkb:autism_spectrum_disorder
schizophrenia
stroke
neurodegenerative diseases
gptkbp:activatedBy gptkb:trauma
infection
gptkbp:activatedState gptkb:M1
gptkb:M2
gptkbp:canRelease cytokines
growth factors
reactive oxygen species
chemokines
gptkbp:discoveredBy gptkb:Pío_del_Río_Hortega
gptkbp:discoveredIn 1919
gptkbp:doNotOriginateFrom bone marrow
monocytes
gptkbp:expressedIn gptkb:TREM2
CX3CR1
P2RY12
gptkbp:firstDescribed rodents
gptkbp:foundIn central nervous system
gptkbp:function phagocytosis
immune surveillance
https://www.w3.org/2000/01/rdf-schema#label microglia
gptkbp:interactsWith gptkb:oligodendrocytes
neurons
astrocytes
gptkbp:lifespan long-lived
gptkbp:marking gptkb:CD11b
Iba1
TMEM119
gptkbp:origin yolk sac progenitors
gptkbp:presentIn humans
mammals
vertebrates
gptkbp:renewable self-renewing
gptkbp:role gptkb:Alzheimer's_disease
gptkb:Parkinson's_disease
multiple sclerosis
brain development
neuroinflammation
synaptic pruning
gptkbp:type macrophage
gptkbp:bfsParent gptkb:Macrophage
gptkbp:bfsLayer 5