Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:complement_receptor_3
gptkb:CD11b/CD18 integrin alphaMbeta2 |
| gptkbp:associatedWith |
autoimmune diseases
immune deficiencies |
| gptkbp:binds |
gptkb:ICAM-1
gptkb:fibrinogen gptkb:iC3b gptkb:LPS gptkb:heparin gptkb:factor_X |
| gptkbp:composedOf |
gptkb:CD11b
gptkb:CD18 |
| gptkbp:discoveredIn |
1980s
|
| gptkbp:encodedBy |
gptkb:ITGAM_gene
gptkb:ITGB2_gene |
| gptkbp:expressedIn |
macrophages
monocytes neutrophils |
| gptkbp:foundIn |
gptkb:leukocytes
|
| gptkbp:function |
immune response
phagocytosis cell adhesion |
| https://www.w3.org/2000/01/rdf-schema#label |
Mac-1 integrin
|
| gptkbp:role |
inflammation
leukocyte migration pathogen recognition |
| gptkbp:target |
therapeutic antibodies
|
| gptkbp:bfsParent |
gptkb:integrin_alpha_M_(CD11b)
gptkb:CD11b |
| gptkbp:bfsLayer |
7
|