Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
integrin beta-2
|
| gptkbp:component |
gptkb:LFA-1
gptkb:Mac-1 alphaLbeta2 integrin alphaMbeta2 integrin alphaXbeta2 integrin p150,95 |
| gptkbp:encodedBy |
gptkb:ITGB2_gene
|
| gptkbp:Entrez_Gene_ID |
3689
|
| gptkbp:expressedIn |
white blood cells
|
| gptkbp:formsHeterodimerWith |
gptkb:CD11c
gptkb:CD11a gptkb:CD11b CD11d |
| gptkbp:foundIn |
gptkb:leukocytes
|
| gptkbp:function |
immune response
cell adhesion mediates leukocyte-endothelial cell interactions |
| gptkbp:HGNC_ID |
6157
|
| https://www.w3.org/2000/01/rdf-schema#label |
CD18
|
| gptkbp:locatedOnChromosome |
21q22.3
|
| gptkbp:molecularWeight |
95 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:leukocyte_adhesion_deficiency
|
| gptkbp:OMIM |
600065
|
| gptkbp:requires |
phagocytosis
neutrophil migration immune cell signaling |
| gptkbp:structure |
transmembrane glycoprotein
|
| gptkbp:UniProtID |
P05107
|
| gptkbp:bfsParent |
gptkb:CR3
gptkb:complement_receptor_3 gptkb:integrin_beta_2_(CD18) gptkb:CD11b |
| gptkbp:bfsLayer |
7
|