|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:CD11b
CR3A
|
|
gptkbp:associatedWith
|
gptkb:systemic_lupus_erythematosus
autoimmune diseases
|
|
gptkbp:biologicalProcess
|
immune response
inflammatory response
receptor activity
integrin binding
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
integrin complex
|
|
gptkbp:complexName
|
gptkb:CR3
gptkb:Mac-1
|
|
gptkbp:encodes
|
Integrin alpha M
|
|
gptkbp:Entrez_Gene_ID
|
3684
ENSG00000169896
|
|
gptkbp:expressedIn
|
gptkb:natural_killer_cells
macrophages
myeloid cells
monocytes
granulocytes
|
|
gptkbp:formsComplexWith
|
gptkb:ITGB2
|
|
gptkbp:function
|
phagocytosis
cell adhesion
leukocyte migration
|
|
gptkbp:HGNC_ID
|
6147
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ITGAM
|
|
gptkbp:locatedOnChromosome
|
gptkb:16p11.2
|
|
gptkbp:mutationAssociatedWith
|
impaired phagocytosis
susceptibility to infection
|
|
gptkbp:OMIM
|
120980
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Itgam
|
|
gptkbp:product
|
CD11b protein
|
|
gptkbp:UniProtID
|
P20702
|
|
gptkbp:bfsParent
|
gptkb:CR3
gptkb:integrin_alpha_M_(CD11b)
gptkb:CD11b
|
|
gptkbp:bfsLayer
|
7
|