|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:CD11b
gptkb:ITGAM
gptkb:Mac-1_alpha_chain
|
|
gptkbp:binds
|
gptkb:ICAM-1
gptkb:fibrinogen
gptkb:iC3b
|
|
gptkbp:component
|
gptkb:CR3_(complement_receptor_3)
gptkb:Mac-1_integrin
|
|
gptkbp:discoveredIn
|
1980s
|
|
gptkbp:encodedBy
|
gptkb:ITGAM_gene
|
|
gptkbp:Entrez_Gene_ID
|
3684
|
|
gptkbp:expressedIn
|
gptkb:natural_killer_cells
dendritic cells
macrophages
monocytes
neutrophils
|
|
gptkbp:formsComplexWith
|
gptkb:integrin_beta_2_(CD18)
|
|
gptkbp:foundIn
|
gptkb:leukocytes
|
|
gptkbp:function
|
immune response
phagocytosis
cell adhesion
|
|
gptkbp:HGNC_ID
|
6156
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
integrin alpha M (CD11b)
|
|
gptkbp:involvedIn
|
innate immunity
complement system
leukocyte migration
|
|
gptkbp:locatedOnChromosome
|
gptkb:16p11.2
|
|
gptkbp:marking
|
inflammation
myeloid cells
|
|
gptkbp:molecularWeight
|
170 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:systemic_lupus_erythematosus
autoimmune diseases
|
|
gptkbp:OMIM
|
120980
|
|
gptkbp:structure
|
type I transmembrane glycoprotein
|
|
gptkbp:subunit
|
gptkb:integrin_alpha-M_beta-2_complex
|
|
gptkbp:target
|
antibodies in flow cytometry
|
|
gptkbp:UniProtID
|
P11215
|
|
gptkbp:bfsParent
|
gptkb:CR3_domain
|
|
gptkbp:bfsLayer
|
6
|