leukocyte adhesion deficiency type 1
GPTKB entity
Statements (21)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
immunodeficiency |
| gptkbp:affects |
immune system
|
| gptkbp:alsoKnownAs |
LAD-1
|
| gptkbp:characterizedBy |
leukocytosis
impaired wound healing recurrent bacterial infections delayed umbilical cord separation |
| gptkbp:deficiencyCauses |
CD18 integrin
|
| gptkbp:diagnosedBy |
flow cytometry
|
| gptkbp:firstDescribed |
1980s
|
| https://www.w3.org/2000/01/rdf-schema#label |
leukocyte adhesion deficiency type 1
|
| gptkbp:inheritance |
autosomal recessive
|
| gptkbp:mutationAssociatedWith |
gptkb:ITGB2_gene
|
| gptkbp:OMIM |
116920
|
| gptkbp:prevalence |
rare
|
| gptkbp:treatment |
antibiotics
bone marrow transplantation |
| gptkbp:bfsParent |
gptkb:integrin_beta_2_(CD18)
gptkb:CD11b |
| gptkbp:bfsLayer |
7
|