ALK

URI: https://gptkb.org/entity/ALK

GPTKB entity

Statements (44)

Predicate	Object
gptkbp:instance_of	gptkb:DNA
gptkbp:associated_with	gptkb:Oncology
gptkbp:code	gptkb:anaplastic_lymphoma_kinase_protein
gptkbp:discovered_by	gptkb:Dr._David_J._J._P._M._van_der_Velden
gptkbp:ecological_role	gptkb:Waldenström's_macroglobulinemia gptkb:primary_mediastinal_B-cell_lymphoma gptkb:idiopathic_pulmonary_fibrosis gptkb:chronic_myeloid_leukemia gptkb:myelodysplastic_syndromes gptkb:Oncology gptkb:Kaposi's_sarcoma gptkb:non-Hodgkin_lymphoma gptkb:pancreatic_cancer gptkb:neuroblastoma gptkb:T-cell_acute_lymphoblastic_leukemia gptkb:T-cell_acute_lymphoblastic_leukemia,_not_otherwise_specified gptkb:T-cell_chronic_lymphocytic_leukemia gptkb:T-cell_large_granular_lymphocyte_leukemia gptkb:T-cell_lymphoblastic_leukemia/lymphoma gptkb:T-cell_lymphoblastic_lymphoma gptkb:T-cell_prolymphocytic_leukemia gptkb:T-cell_rich_B-cell_lymphoma gptkb:adult_T-cell_leukemia/lymphoma gptkb:anaplastic_large_cell_lymphoma,_ALK-negative gptkb:anaplastic_large_cell_lymphoma,_ALK-positive gptkb:lymphoblastic_lymphoma ovarian cancer stomach cancer esophageal cancer head and neck cancer MDS/ MPN overlap syndromes T-cell acute lymphoblastic leukemia, with t(5;14)(q35;q32)
gptkbp:genetic_studies	rearrangement
https://www.w3.org/2000/01/rdf-schema#label	ALK
gptkbp:interacts_with	gptkb:EML4
gptkbp:involved_in	cell signaling
gptkbp:is_recognized_as	gptkb:1994
gptkbp:is_targeted_at	gptkb:alectinib gptkb:ceritinib gptkb:crizotinib
gptkbp:located_in	chromosome 2
gptkbp:bfsParent	gptkb:Alaska_Air_Group gptkb:Sri_Lankan_Airlines
gptkbp:bfsLayer	5