anaplastic lymphoma kinase

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein gptkb:enzyme
gptkbp:alternativeName	gptkb:CD246 gptkb:ALK
gptkbp:associatedWith	gptkb:anaplastic_large_cell_lymphoma gptkb:neuroblastoma gptkb:non-small_cell_lung_cancer
gptkbp:biologicalProcess	ATP binding protein tyrosine kinase activity
gptkbp:cellularComponent	gptkb:cytoplasm gptkb:plasma_membrane
gptkbp:discoveredBy	gptkb:Steven_A._Morris
gptkbp:discoveredIn	1994
gptkbp:EC_number	2.7.10.1
gptkbp:encodedBy	gptkb:ALK_gene
gptkbp:Entrez_Gene_ID	238
gptkbp:function	gptkb:receptor_tyrosine_kinase cell growth regulation
gptkbp:gene	gptkb:ALK
gptkbp:HGNC_ID	427
gptkbp:locatedOnChromosome	chromosome 2 2p23
gptkbp:mutationAssociatedWith	gptkb:gene gptkb:point_mutation
gptkbp:OMIM	105590
gptkbp:PDB	gptkb:3LCS
gptkbp:species	gptkb:Homo_sapiens
gptkbp:targetOfDrug	gptkb:alectinib gptkb:ceritinib gptkb:crizotinib gptkb:lorlatinib
gptkbp:UniProtID	gptkb:Q9UM73
gptkbp:bfsParent	gptkb:ALK
gptkbp:bfsLayer	6
https://www.w3.org/2000/01/rdf-schema#label	anaplastic lymphoma kinase