CD246

URI: https://gptkb.org/entity/CD246

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alsoKnownAs	gptkb:ALK
gptkbp:associatedWith	gptkb:anaplastic_large_cell_lymphoma gptkb:neuroblastoma gptkb:non-small_cell_lung_cancer
gptkbp:discoveredBy	gptkb:Steven_Morris
gptkbp:discoveredIn	1994
gptkbp:encodedBy	gptkb:ALK_gene
gptkbp:Entrez_Gene_ID	ENSG00000171094
gptkbp:expressedIn	gptkb:nervous_system
gptkbp:fullName	gptkb:Anaplastic_lymphoma_kinase
gptkbp:function	gptkb:receptor_tyrosine_kinase
gptkbp:gene	gptkb:ALK_gene
gptkbp:HGNC_ID	427
https://www.w3.org/2000/01/rdf-schema#label	CD246
gptkbp:locatedOnChromosome	chromosome 2p23
gptkbp:location	gptkb:cell_membrane
gptkbp:mutationAssociatedWith	gptkb:protein point mutation
gptkbp:OMIM	105590
gptkbp:role	cell differentiation cell growth oncogenesis
gptkbp:target	gptkb:alectinib gptkb:brigatinib gptkb:ceritinib gptkb:crizotinib gptkb:lorlatinib
gptkbp:UniProtID	gptkb:Q9UM73
gptkbp:bfsParent	gptkb:ALK
gptkbp:bfsLayer	6