Statements (25)
Predicate | Object |
---|---|
gptkbp:instance_of |
gptkb:pharmaceuticals
|
gptkbp:administered_by |
oral tablet
|
gptkbp:approves |
gptkb:FDA
|
gptkbp:atccode |
L01 XE34
|
gptkbp:brand |
Alunbrig
|
gptkbp:casnumber |
1195760-78-6
|
gptkbp:chemical_formula |
C22 H24 Cl N5 O2 S
|
gptkbp:clinical_trial |
Phase 2
|
gptkbp:developed_by |
gptkb:ARIAD_Pharmaceuticals
|
gptkbp:dosage_form |
250 mg tablet
|
gptkbp:effective_date |
gptkb:2017
|
https://www.w3.org/2000/01/rdf-schema#label |
brigatinib
|
gptkbp:mechanism_of_action |
ALK inhibitor
|
gptkbp:route_of_administration |
oral
|
gptkbp:side_effect |
fatigue
headache nausea diarrhea elevated liver enzymes |
gptkbp:targets |
gptkb:anaplastic_lymphoma_kinase_(ALK)
|
gptkbp:used_for |
gptkb:Oncology
|
gptkbp:bfsParent |
gptkb:ALK_gene_rearrangements
gptkb:JAK1 gptkb:anaplastic_lymphoma_kinase_protein |
gptkbp:bfsLayer |
7
|