alectinib

GPTKB entity

Statements (25)
Predicate Object
gptkbp:instance_of gptkb:drug
gptkbp:activities inhibitor of anaplastic lymphoma kinase (ALK)
gptkbp:appointed_by oral tablet
gptkbp:approves gptkb:2015
gptkb:FDA
gptkbp:clinical_trial Phase II
Phase III
approximately 50%
Phase I
gptkbp:developed_by gptkb:Roche
https://www.w3.org/2000/01/rdf-schema#label alectinib
gptkbp:ingredients C22 H24 Cl N5 O2 S
gptkbp:is_atype_of L01 X E34
gptkbp:is_used_for treatment of non-small cell lung cancer
gptkbp:manager oral
gptkbp:marketed_as gptkb:Alecensa
gptkbp:side_effect fatigue
muscle pain
nausea
constipation
liver enzyme elevation
gptkbp:targets gptkb:ALK_gene_rearrangements
gptkbp:type_of 1195767-69-0
gptkbp:bfsParent gptkb:ALK
gptkbp:bfsLayer 5