|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:FOXO4
Forkhead box O4
|
|
gptkbp:binds
|
gptkb:gene
|
|
gptkbp:domain
|
transactivation domain
forkhead box domain
nuclear export signal
nuclear localization signal
|
|
gptkbp:encodedBy
|
gptkb:FOXO4_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000184481
4303
|
|
gptkbp:expressedIn
|
various human tissues
|
|
gptkbp:function
|
transcription factor
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:3817
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
AFX (FOXO4)
|
|
gptkbp:inhibitedBy
|
gptkb:PI3K/AKT_pathway
|
|
gptkbp:interactsWith
|
gptkb:14-3-3_proteins
gptkb:CBP/p300
gptkb:p53
gptkb:SMAD_proteins
|
|
gptkbp:involves
|
gptkb:cancer
gptkb:diabetes
aging
|
|
gptkbp:locatedOnChromosome
|
Xq13.1
|
|
gptkbp:memberOf
|
gptkb:FOXO_subfamily
forkhead family of transcription factors
|
|
gptkbp:mutationAssociatedWith
|
gptkb:rhabdomyosarcoma
leukemia
|
|
gptkbp:orthologInMouse
|
gptkb:Foxo4
|
|
gptkbp:phosphorylates
|
gptkb:AKT1
gptkb:SGK
|
|
gptkbp:regulates
|
apoptosis
DNA repair
cellular senescence
growth factors
cell cycle
oxidative stress response
insulin signaling
oxidative stress
nutrient availability
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:translocationPartner
|
gptkb:MLL_gene
PAX3 gene
PAX7 gene
|
|
gptkbp:UniProtID
|
P98177
|
|
gptkbp:bfsParent
|
gptkb:FOXO
|
|
gptkbp:bfsLayer
|
7
|