Foxo4

GPTKB entity

Statements (49)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alias gptkb:AFX
gptkb:AFX1
MSTP037
gptkbp:associatedWith gptkb:cancer
aging
gptkbp:binds gptkb:gene
gptkbp:encodes gptkb:Forkhead_box_protein_O4
gptkbp:Entrez_Gene_ID gptkb:ENSG00000184481
4303
gptkbp:expressedIn various tissues
gptkbp:function transcription factor
https://www.w3.org/2000/01/rdf-schema#label Foxo4
gptkbp:inhibitedBy gptkb:PI3K/AKT_pathway
gptkbp:length 505 amino acids
gptkbp:locatedOnChromosome gptkb:X_chromosome
gptkbp:memberOf gptkb:FOXO_subfamily
forkhead family of transcription factors
gptkbp:molecularWeight 55 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse gptkb:Foxo4
gptkbp:phosphorylates gptkb:AKT1
gptkbp:regulates apoptosis
cell proliferation
cell survival
DNA repair
lipid metabolism
metabolism
cellular senescence
angiogenesis
cell migration
muscle atrophy
glucose metabolism
inflammation
immune response
oxidative phosphorylation
cell cycle
stem cell maintenance
autophagy
tumor suppression
oxidative stress response
insulin signaling
cellular differentiation
stress resistance
gptkbp:subcellularLocation gptkb:nucleus
gptkb:cytoplasm
gptkbp:UniProtID Q07889
gptkbp:bfsParent gptkb:FOXO4
gptkbp:bfsLayer 7