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gptkbp:instanceOf
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gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:HSP90A
gptkb:HSPC1
gptkb:HSPCA
gptkb:HSP_86
gptkb:HSP_90
|
|
gptkbp:associatedWith
|
gptkb:heat_shock_protein_90_alpha_family_class_A_member_1
|
|
gptkbp:encodes
|
gptkb:HSP90AA1
|
|
gptkbp:Entrez_Gene_ID
|
3320
ENSG00000140403
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:function
|
protein folding
cellular stress response
molecular chaperone
|
|
gptkbp:gene
|
gptkb:HSP90AA1
|
|
gptkbp:HGNC_ID
|
HGNC:5243
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
14q32.33 (HSP90AA1)
|
|
gptkbp:involvedIn
|
signal transduction
protein degradation
apoptosis regulation
cell cycle control
response to heat shock
|
|
gptkbp:length
|
732 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_14
14q32.33
|
|
gptkbp:molecularWeight
|
84 kDa
|
|
gptkbp:mutationAssociatedWith
|
cancer progression
drug resistance
|
|
gptkbp:OMIM
|
140571
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Hsp90aa1
|
|
gptkbp:orthologInYeast
|
gptkb:HSP82
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
protein processing in endoplasmic reticulum
|
|
gptkbp:regulates
|
induced by heat shock
regulated by HSF1
|
|
gptkbp:relatedTo
|
gptkb:cancer
neurodegenerative diseases
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
extracellular exosome
|
|
gptkbp:target
|
gptkb:HSP90_inhibitors
gptkb:17-AAG
gptkb:geldanamycin
|
|
gptkbp:UniProtID
|
gptkb:P07900
|
|
gptkbp:bfsParent
|
gptkb:HSP90
|
|
gptkbp:bfsLayer
|
7
|