|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:heat_shock_protein_90_alpha_family_class_A_member_1
gptkb:HSP90AA1
|
|
gptkbp:discoveredBy
|
gptkb:Ferruccio_Ritossa
|
|
gptkbp:discoveredIn
|
1962
|
|
gptkbp:encodedBy
|
HSP90AA1 gene
|
|
gptkbp:ensembl
|
gptkb:ENSG00000080824
|
|
gptkbp:Entrez_Gene_ID
|
3320
|
|
gptkbp:expressedIn
|
ubiquitous
|
|
gptkbp:function
|
protein folding
cellular stress response
molecular chaperone
|
|
gptkbp:gene
|
gptkb:HSP90AA1
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HSPC1
|
|
gptkbp:interactsWith
|
gptkb:HSP70
gptkb:AHA1
gptkb:CDC37
|
|
gptkbp:involvedIn
|
signal transduction
protein degradation
cell cycle control
|
|
gptkbp:locatedOnChromosome
|
14q32.31
|
|
gptkbp:location
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:mainTerminal
|
GO:0005524
GO:0006457
GO:0006950
|
|
gptkbp:molecularWeight
|
~90 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
2CG9
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
acetylation
|
|
gptkbp:RefSeq
|
NM_005348
|
|
gptkbp:significance
|
gptkb:cancer
neurodegenerative diseases
|
|
gptkbp:target
|
gptkb:17-AAG
gptkb:geldanamycin
|
|
gptkbp:UniProtID
|
gptkb:P07900
|
|
gptkbp:bfsParent
|
gptkb:14q32.33_(HSP90AA1)
gptkb:HSP90AA1
|
|
gptkbp:bfsLayer
|
8
|