Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:HSP90
Heat Shock Protein 90kDa |
| gptkbp:ATPaseActivity |
yes
|
| gptkbp:coChaperone |
gptkb:HOP
gptkb:CDC37 p23 |
| gptkbp:conservedIn |
eukaryotes
|
| gptkbp:foundIn |
eukaryotic cells
|
| gptkbp:fullName |
gptkb:Heat_Shock_Protein_90
|
| gptkbp:function |
molecular chaperone
|
| gptkbp:gene |
gptkb:HSP90AA1
gptkb:HSP90AB1 |
| https://www.w3.org/2000/01/rdf-schema#label |
HSP 90
|
| gptkbp:inhibitedBy |
gptkb:geldanamycin
gptkb:radicicol |
| gptkbp:interactsWith |
client proteins
|
| gptkbp:involvedIn |
protein folding
cellular stress response |
| gptkbp:locale |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:molecularWeight |
~90 kDa
|
| gptkbp:role |
signal transduction
protein degradation cancer cell survival |
| gptkbp:structure |
homodimer
|
| gptkbp:bfsParent |
gptkb:14q32.33_(HSP90AA1)
|
| gptkbp:bfsLayer |
8
|