Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:antibiotic
gptkb:benzoquinone_ansamycin |
| gptkbp:ATCCode |
L01XX25
|
| gptkbp:CASNumber |
gptkb:30562-34-6
|
| gptkbp:color |
yellow
|
| gptkbp:discoveredIn |
1970
|
| gptkbp:hasBiologicalActivity |
antibacterial
antitumor |
| gptkbp:hasMolecularFormula |
C29H40N2O9
|
| https://www.w3.org/2000/01/rdf-schema#label |
geldanamycin
|
| gptkbp:inhibitedBy |
gptkb:Hsp90
|
| gptkbp:isCytotoxic |
true
|
| gptkbp:IUPACName |
(3R,4E,6S,7R,8E,10R,11R,12R,13S,14R,16R)-13-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-3-methoxy-6-methyloxan-2-yl]oxy-7,12,14-trimethoxy-3,6,10,12,16-pentamethyl-1,17-dioxabicyclo[14.1.0]heptadeca-4,8-diene-2,15-dione
|
| gptkbp:meltingPoint |
178-180°C
|
| gptkbp:notableDerivative |
gptkb:17-DMAG
gptkb:17-AAG |
| gptkbp:producedBy |
gptkb:Streptomyces_hygroscopicus
|
| gptkbp:PubChem_CID |
gptkb:CHEMBL413
5288382 |
| gptkbp:sideEffect |
hepatotoxicity
|
| gptkbp:target |
gptkb:heat_shock_protein_90
|
| gptkbp:usedIn |
cancer research
|
| gptkbp:bfsParent |
gptkb:HSP90
gptkb:Streptomyces_hygroscopicus gptkb:Hsp90 |
| gptkbp:bfsLayer |
7
|