type III receptor tyrosine kinase family
GPTKB entity
Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
PDGFR family
|
| gptkbp:contains |
extracellular immunoglobulin-like domains
split intracellular kinase domain |
| gptkbp:discoveredBy |
molecular biology research
|
| gptkbp:foundIn |
vertebrates
|
| gptkbp:function |
cell signaling
regulation of cell differentiation regulation of cell proliferation regulation of cell survival |
| https://www.w3.org/2000/01/rdf-schema#label |
type III receptor tyrosine kinase family
|
| gptkbp:ligand |
gptkb:platelet-derived_growth_factor
gptkb:stem_cell_factor Fms-like tyrosine kinase 3 ligand colony stimulating factor 1 |
| gptkbp:member |
gptkb:PDGFRA
gptkb:PDGFRB gptkb:KIT gptkb:FLT3 gptkb:CSF1R |
| gptkbp:mutationAssociatedWith |
gptkb:gastrointestinal_stromal_tumor
gptkb:mastocytosis gptkb:cancer gptkb:acute_myeloid_leukemia |
| gptkbp:bfsParent |
gptkb:c-KIT
|
| gptkbp:bfsLayer |
7
|