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tumor necrosis factor superfamily
URI:
https://gptkb.org/entity/tumor_necrosis_factor_superfamily
GPTKB entity
Statements (50)
Predicate
Object
gptkbp:instanceOf
gptkb:protein
gptkbp:abbreviation
TNF superfamily
gptkbp:category
cytokines
gptkbp:composedOf
gptkb:Fas_ligand
gptkb:APRIL
gptkb:tumor_necrosis_factor_beta
gptkb:tumor_necrosis_factor_alpha
gptkb:lymphotoxin_alpha
gptkb:lymphotoxin_beta
gptkb:TRAIL
gptkb:CD40_ligand
gptkb:BAFF
gptkb:RANKL
gptkb:TWEAK
gptkbp:discoveredIn
1975
gptkbp:encodedBy
TNFSF genes
gptkbp:foundIn
vertebrates
gptkbp:function
cell differentiation
cell proliferation
inflammation
cell death
regulation of immune system
induction of apoptosis
gptkbp:GO_term
gptkb:GO:0005125
gptkbp:hasMember
gptkb:TNFSF13
gptkb:TNFSF6
gptkb:TNFSF3
gptkb:TNFSF13B
TNFSF2
TNFSF1
TNFSF10
TNFSF11
TNFSF12
TNFSF14
TNFSF15
TNFSF18
TNFSF4
TNFSF5
TNFSF7
TNFSF8
TNFSF9
https://www.w3.org/2000/01/rdf-schema#label
tumor necrosis factor superfamily
gptkbp:receptorFamily
gptkb:tumor_necrosis_factor_receptor_superfamily
gptkbp:relatedTo
gptkb:cancer
autoimmune diseases
inflammatory diseases
gptkbp:structure
soluble proteins
type II transmembrane proteins
gptkbp:bfsParent
gptkb:Lymphotoxin_alpha
gptkbp:bfsLayer
6