tumor necrosis factor superfamily

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:abbreviation TNF superfamily
gptkbp:category cytokines
gptkbp:composedOf gptkb:Fas_ligand
gptkb:APRIL
gptkb:tumor_necrosis_factor_beta
gptkb:tumor_necrosis_factor_alpha
gptkb:lymphotoxin_alpha
gptkb:lymphotoxin_beta
gptkb:TRAIL
gptkb:CD40_ligand
gptkb:BAFF
gptkb:RANKL
gptkb:TWEAK
gptkbp:discoveredIn 1975
gptkbp:encodedBy TNFSF genes
gptkbp:foundIn vertebrates
gptkbp:function cell differentiation
cell proliferation
inflammation
cell death
regulation of immune system
induction of apoptosis
gptkbp:GO_term gptkb:GO:0005125
gptkbp:hasMember gptkb:TNFSF13
gptkb:TNFSF6
gptkb:TNFSF3
gptkb:TNFSF13B
TNFSF2
TNFSF1
TNFSF10
TNFSF11
TNFSF12
TNFSF14
TNFSF15
TNFSF18
TNFSF4
TNFSF5
TNFSF7
TNFSF8
TNFSF9
https://www.w3.org/2000/01/rdf-schema#label tumor necrosis factor superfamily
gptkbp:receptorFamily gptkb:tumor_necrosis_factor_receptor_superfamily
gptkbp:relatedTo gptkb:cancer
autoimmune diseases
inflammatory diseases
gptkbp:structure soluble proteins
type II transmembrane proteins
gptkbp:bfsParent gptkb:Lymphotoxin_alpha
gptkbp:bfsLayer 6