tumor necrosis factor superfamily

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:abbreviation	TNF superfamily
gptkbp:category	cytokines
gptkbp:composedOf	gptkb:Fas_ligand gptkb:APRIL gptkb:tumor_necrosis_factor_beta gptkb:tumor_necrosis_factor_alpha gptkb:lymphotoxin_alpha gptkb:lymphotoxin_beta gptkb:TRAIL gptkb:CD40_ligand gptkb:BAFF gptkb:RANKL gptkb:TWEAK
gptkbp:discoveredIn	1975
gptkbp:encodedBy	TNFSF genes
gptkbp:foundIn	vertebrates
gptkbp:function	cell differentiation cell proliferation inflammation cell death regulation of immune system induction of apoptosis
gptkbp:GO_term	gptkb:GO:0005125
gptkbp:hasMember	gptkb:TNFSF13 gptkb:TNFSF6 gptkb:TNFSF3 gptkb:TNFSF13B TNFSF2 TNFSF1 TNFSF10 TNFSF11 TNFSF12 TNFSF14 TNFSF15 TNFSF18 TNFSF4 TNFSF5 TNFSF7 TNFSF8 TNFSF9
gptkbp:receptorFamily	gptkb:tumor_necrosis_factor_receptor_superfamily
gptkbp:relatedTo	gptkb:cancer autoimmune diseases inflammatory diseases
gptkbp:structure	soluble proteins type II transmembrane proteins
gptkbp:bfsParent	gptkb:Fas_ligand gptkb:tumor_necrosis_factor_ligand_superfamily gptkb:LTX-β
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	tumor necrosis factor superfamily