|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
Apo-2L
CD253
|
|
gptkbp:discoveredBy
|
Wiley et al.
|
|
gptkbp:discoveredIn
|
1995
|
|
gptkbp:encodedBy
|
TNFSF10 gene
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:fullName
|
TNF-related apoptosis-inducing ligand
|
|
gptkbp:function
|
induces apoptosis
regulates immune response
|
|
gptkbp:gene
|
TNFSF10
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TRAIL
|
|
gptkbp:inducedBy
|
caspase activation
|
|
gptkbp:involvedIn
|
immune surveillance
cell death signaling pathway
|
|
gptkbp:locatedOnChromosome
|
chromosome 3q26
|
|
gptkbp:memberOf
|
tumor necrosis factor ligand family
|
|
gptkbp:molecularWeight
|
32 kDa
|
|
gptkbp:OMIM
|
603598
|
|
gptkbp:orthologIn
|
mouse Tnfsf10
|
|
gptkbp:recipient
|
gptkb:DR4
gptkb:DR5
DcR1
DcR2
osteoprotegerin
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:structure
|
type II transmembrane protein
|
|
gptkbp:UniProtID
|
P50591
|
|
gptkbp:usedIn
|
cancer therapy research
|
|
gptkbp:bfsParent
|
gptkb:tumor_necrosis_factor_ligand_superfamily
gptkb:tumor_necrosis_factor_superfamily
gptkb:DR5
gptkb:Fas_ligand_(FasL)
gptkb:TNF_receptor_superfamily
|
|
gptkbp:bfsLayer
|
7
|