TWEAK

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName CD255
gptkbp:associatedWith gptkb:cancer
autoimmune diseases
inflammatory diseases
gptkbp:discoveredBy 1997
gptkbp:encodedBy TNFSF12 gene
gptkbp:expressedIn various tissues
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:fullName Tumor necrosis factor-like weak inducer of apoptosis
gptkbp:function induces apoptosis
regulates cell proliferation
regulates inflammation
gptkbp:gene TNFSF12
gptkbp:HGNC_ID 11942
https://www.w3.org/2000/01/rdf-schema#label TWEAK
gptkbp:locatedOnChromosome 17p13.1
gptkbp:memberOf gptkb:tumor_necrosis_factor_(TNF)_ligand_family
gptkbp:molecularWeight ~30 kDa
gptkbp:OMIM 603246
gptkbp:recipient Fn14
gptkbp:regulates angiogenesis
cell migration
tissue regeneration
gptkbp:structure type II transmembrane protein
gptkbp:UniProtID O43508
gptkbp:bfsParent gptkb:tumor_necrosis_factor_superfamily
gptkbp:bfsLayer 7