|
gptkbp:instanceOf
|
gptkb:protein
cytokine
|
|
gptkbp:alternativeName
|
gptkb:TNF-beta
tumor necrosis factor-beta
|
|
gptkbp:associatedWith
|
gptkb:cancer
autoimmune diseases
rheumatoid arthritis
inflammatory bowel disease
|
|
gptkbp:discoveredBy
|
T. A. Carswell et al.
|
|
gptkbp:discoveredIn
|
1975
|
|
gptkbp:encodedBy
|
gptkb:LTA_gene
|
|
gptkbp:Entrez_Gene_ID
|
4049
|
|
gptkbp:expressedIn
|
activated lymphocytes
|
|
gptkbp:formsComplexWith
|
gptkb:lymphotoxin_beta
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
regulation of immune response
induction of cell death
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
lymphotoxin alpha
|
|
gptkbp:length
|
171 amino acids
|
|
gptkbp:locatedOnChromosome
|
chromosome 6p21.3
|
|
gptkbp:memberOf
|
gptkb:tumor_necrosis_factor_superfamily
|
|
gptkbp:OMIM
|
153440
|
|
gptkbp:recipient
|
gptkb:TNFRSF1A
gptkb:TNFRSF1B
|
|
gptkbp:regulates
|
apoptosis
inflammation
lymphoid organ development
|
|
gptkbp:secretes
|
secreted protein
|
|
gptkbp:structure
|
homotrimer
|
|
gptkbp:UniProtID
|
P01374
|
|
gptkbp:bfsParent
|
gptkb:tumor_necrosis_factor_superfamily
gptkb:MHC_class_III_molecules
gptkb:TNF-beta
|
|
gptkbp:bfsLayer
|
7
|