|
gptkbp:instanceOf
|
gptkb:cytokine
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Apo-1_ligand
gptkb:CD95L
gptkb:TNFSF6
|
|
gptkbp:binds
|
gptkb:Fas_receptor
|
|
gptkbp:cleavage
|
gptkb:matrix_metalloproteinases
|
|
gptkbp:discoveredIn
|
1993
|
|
gptkbp:encodedBy
|
gptkb:FASLG_gene
|
|
gptkbp:Entrez_Gene_ID
|
356
|
|
gptkbp:expressedIn
|
gptkb:natural_killer_cells
activated T cells
some epithelial cells
|
|
gptkbp:foundIn
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:function
|
induces apoptosis
|
|
gptkbp:inducedBy
|
caspase activation
|
|
gptkbp:involvedIn
|
gptkb:cancer
gptkb:graft-versus-host_disease
autoimmune diseases
|
|
gptkbp:locatedOnChromosome
|
1q23
|
|
gptkbp:memberOf
|
gptkb:tumor_necrosis_factor_superfamily
|
|
gptkbp:molecularWeight
|
40 kDa
|
|
gptkbp:OMIM
|
134638
|
|
gptkbp:produces
|
gptkb:soluble_Fas_ligand
|
|
gptkbp:regulates
|
lymphocyte homeostasis
|
|
gptkbp:role
|
immune system regulation
activation-induced cell death
|
|
gptkbp:structure
|
type-II transmembrane protein
|
|
gptkbp:UniProtID
|
gptkb:P48023
|
|
gptkbp:bfsParent
|
gptkb:Fas
gptkb:Fas_receptor
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Fas ligand
|