|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:CD154
|
|
gptkbp:binds
|
gptkb:CD40
|
|
gptkbp:discoveredIn
|
1992
|
|
gptkbp:encodedBy
|
CD40LG gene
|
|
gptkbp:Entrez_Gene_ID
|
959
CD40LG
ENSG00000102245
|
|
gptkbp:expressedIn
|
platelets
activated T cells
|
|
gptkbp:function
|
T cell activation
immune system regulation
B cell activation
immunoglobulin class switching
|
|
gptkbp:HGNC_ID
|
11935
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CD40 ligand
|
|
gptkbp:involvedIn
|
autoimmune diseases
inflammatory response
|
|
gptkbp:locatedOnChromosome
|
Xq26
|
|
gptkbp:memberOf
|
gptkb:tumor_necrosis_factor_superfamily
|
|
gptkbp:molecularWeight
|
33 kDa
|
|
gptkbp:mutationAssociatedWith
|
X-linked hyper-IgM syndrome
|
|
gptkbp:OMIM
|
300386
|
|
gptkbp:orthologInMouse
|
Cd40lg
|
|
gptkbp:PDB
|
1ALY
|
|
gptkbp:structure
|
type II transmembrane protein
|
|
gptkbp:target
|
therapeutic antibodies
|
|
gptkbp:UniProtID
|
P29965
|
|
gptkbp:bfsParent
|
gptkb:tumor_necrosis_factor_ligand_superfamily
gptkb:tumor_necrosis_factor_superfamily
gptkb:TNF_receptor_superfamily
|
|
gptkbp:bfsLayer
|
7
|