Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alsoKnownAs |
gptkb:CD154
|
| gptkbp:binds |
gptkb:CD40
|
| gptkbp:discoveredIn |
1992
|
| gptkbp:encodedBy |
CD40LG gene
|
| gptkbp:Entrez_Gene_ID |
959
CD40LG ENSG00000102245 |
| gptkbp:expressedIn |
platelets
activated T cells |
| gptkbp:function |
T cell activation
immune system regulation B cell activation immunoglobulin class switching |
| gptkbp:HGNC_ID |
11935
|
| gptkbp:involvedIn |
autoimmune diseases
inflammatory response |
| gptkbp:locatedOnChromosome |
Xq26
|
| gptkbp:memberOf |
gptkb:tumor_necrosis_factor_superfamily
|
| gptkbp:molecularWeight |
33 kDa
|
| gptkbp:mutationAssociatedWith |
X-linked hyper-IgM syndrome
|
| gptkbp:OMIM |
300386
|
| gptkbp:orthologInMouse |
Cd40lg
|
| gptkbp:PDB |
1ALY
|
| gptkbp:structure |
type II transmembrane protein
|
| gptkbp:target |
therapeutic antibodies
|
| gptkbp:UniProtID |
P29965
|
| gptkbp:bfsParent |
gptkb:tumor_necrosis_factor_ligand_superfamily
gptkb:TNF_receptor_superfamily |
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
CD40 ligand
|