rhodopsin-like GPCR family

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:activatedBy	G protein coupling
gptkbp:alsoKnownAs	gptkb:Class_A_GPCRs
gptkbp:contains	gptkb:rhodopsin gptkb:cannabinoid_receptors gptkb:adenosine_receptors gptkb:opioid_receptors gptkb:angiotensin_receptors gptkb:melatonin_receptors gptkb:muscarinic_acetylcholine_receptors gptkb:trace_amine-associated_receptors gptkb:vasopressin_receptors adrenergic receptors dopamine receptors histamine receptors serotonin receptors olfactory receptors
gptkbp:discoveredBy	gptkb:Robert_J._Lefkowitz
gptkbp:example	gptkb:beta-adrenergic_receptor gptkb:A2A_adenosine_receptor gptkb:5-HT1A_receptor gptkb:mu-opioid_receptor CB1 cannabinoid receptor AT1 angiotensin receptor D2 dopamine receptor H1 histamine receptor M2 muscarinic receptor MT1 melatonin receptor V1 vasopressin receptor
gptkbp:foundIn	animals humans
gptkbp:function	signal transduction
gptkbp:GO_term	GO:0004930
https://www.w3.org/2000/01/rdf-schema#label	rhodopsin-like GPCR family
gptkbp:InterPro	IPR000276
gptkbp:ligand	light lipids nucleotides amines peptides
gptkbp:majorDrugTarget	yes
gptkbp:NobelPrizeYear	gptkb:2012_Nobel_Prize_in_Chemistry
gptkbp:numberOfMembers	over 700 in humans
gptkbp:proteinFamily	PF00001
gptkbp:structure	seven transmembrane helices
gptkbp:subclassOf	gptkb:G_protein-coupled_receptor
gptkbp:bfsParent	gptkb:CCK-B_receptor gptkb:neuropeptide_Y_receptor_Y1
gptkbp:bfsLayer	7