rhodopsin

GPTKB entity

Statements (51)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:G_protein-coupled_receptor
gptkbp:absorption_maximum ~498 nm
gptkbp:activatedBy light
gptkbp:alternativeName visual purple
gptkbp:chromophore gptkb:11-cis-retinal
gptkbp:deactivatedBy phosphorylation
arrestin binding
gptkbp:degradedBy lysosomal proteases
gptkbp:discoveredBy gptkb:Franz_Boll
gptkbp:discoveredIn 1876
gptkbp:EC_number 7.1.1.1
gptkbp:Entrez_Gene_ID ENSG00000163914
gptkbp:expressedIn vertebrates
gptkbp:form gptkb:opsin
gptkb:all-trans-retinal
gptkb:metarhodopsin_II
gptkbp:foundIn retina
rod cells
gptkbp:function photoreceptor activity
gptkbp:gene gptkb:RHO
gptkbp:GO_term GO:0007602
gptkbp:HGNC_ID 10012
https://www.w3.org/2000/01/rdf-schema#label rhodopsin
gptkbp:ligand retinal
gptkbp:location outer segment of rod cells
gptkbp:molecularWeight ~40 kDa
gptkbp:mutationAssociatedWith retinitis pigmentosa
congenital stationary night blindness
gptkbp:OMIM 180380
gptkbp:orthologIn gptkb:bacteriorhodopsin
gptkb:melanopsin
cone opsins
gptkbp:PDB 1F88
gptkbp:postTranslationalModification palmitoylation
phosphorylation
glycosylation
gptkbp:RefSeq NM_000539
gptkbp:relatedTo night vision
color vision
phototransduction
gptkbp:roleInVision scotopic vision
gptkbp:species gptkb:Bos_taurus
gptkb:Mus_musculus
gptkb:Homo_sapiens
gptkbp:structure seven transmembrane helices
gptkbp:subcellularLocation gptkb:plasma_membrane
gptkbp:UniProtID P08100
gptkbp:bfsParent gptkb:G_protein-coupled_receptor
gptkb:G_protein-coupled_receptors
gptkbp:bfsLayer 5