|
gptkbp:instanceOf
|
gptkb:protein
gptkb:G_protein-coupled_receptor
|
|
gptkbp:activatedBy
|
gptkb:Gs_protein
|
|
gptkbp:alternativeName
|
gptkb:ADORA2A
gptkb:Adenosine_A2A_receptor
A2A receptor
A2AR
A2aR
|
|
gptkbp:associatedWith
|
gptkb:Parkinson's_disease
inflammation
ischemia
|
|
gptkbp:binds
|
gptkb:adenosine
|
|
gptkbp:determines
|
X-ray crystallography
|
|
gptkbp:encodedBy
|
ADORA2A gene
|
|
gptkbp:enemyOf
|
gptkb:regadenoson
caffeine
CGS-21680
istradefylline
|
|
gptkbp:expressedIn
|
brain
heart
immune cells
|
|
gptkbp:family
|
adenosine receptor family
|
|
gptkbp:formsComplexWith
|
dopamine D2 receptor
|
|
gptkbp:foundIn
|
gptkb:striatum
|
|
gptkbp:HGNC_ID
|
gptkb:ADORA2A
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
A2A adenosine receptor
|
|
gptkbp:improves
|
cAMP production
|
|
gptkbp:involvedIn
|
immune response
neurotransmission
vasodilation
|
|
gptkbp:length
|
410
|
|
gptkbp:locatedIn
|
gptkb:cell_membrane
|
|
gptkbp:locatedOnChromosome
|
22q11.23
|
|
gptkbp:modulatedBy
|
dopamine signaling
|
|
gptkbp:molecularWeight
|
45 kDa
|
|
gptkbp:OMIM
|
102776
|
|
gptkbp:orthologIn
|
gptkb:mouse
gptkb:zebrafish
right
|
|
gptkbp:PDB
|
3EML
|
|
gptkbp:regulates
|
sleep
motor control
immune cell activity
|
|
gptkbp:subspecies
|
gptkb:adenosine_receptor
|
|
gptkbp:target
|
pharmacological drugs
|
|
gptkbp:UniProtID
|
P29274
|
|
gptkbp:bfsParent
|
gptkb:adenosine_receptor
|
|
gptkbp:bfsLayer
|
6
|