Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:G_protein-coupled_receptor
|
| gptkbp:binds |
gptkb:adenosine
|
| gptkbp:discoveredIn |
1970s
|
| gptkbp:encodedBy |
ADORA2A gene
ADORA1 gene ADORA2B gene ADORA3 gene |
| gptkbp:enemyOf |
gptkb:theophylline
caffeine theobromine |
| gptkbp:expressedIn |
gptkb:cancer
gptkb:bone retina central nervous system liver adipose tissue platelets intestine vascular endothelium peripheral tissues smooth muscle cells |
| gptkbp:foundIn |
gptkb:kidney
brain heart human body immune cells |
| https://www.w3.org/2000/01/rdf-schema#label |
adenosine receptors
|
| gptkbp:involvedIn |
pain modulation
inflammation sleep regulation neuroprotection vasodilation |
| gptkbp:modulatedBy |
adenylate cyclase activity
cyclic AMP levels phospholipase C activity |
| gptkbp:regulates |
immune response
neurotransmitter release cardiac function renal blood flow |
| gptkbp:subclassOf |
purinergic receptor
|
| gptkbp:subspecies |
A2A receptor
A2B receptor A1 receptor A3 receptor |
| gptkbp:target |
antipsychotics
anti-inflammatory drugs pharmacological drugs cardioprotective agents |
| gptkbp:bfsParent |
gptkb:C00242
gptkb:adenosine |
| gptkbp:bfsLayer |
7
|