beta-adrenergic receptor

GPTKB entity

Statements (43)
Predicate Object
gptkbp:instanceOf gptkb:cell_membrane
gptkb:G_protein-coupled_receptor
gptkbp:activatedBy gptkb:catecholamines
gptkbp:associatedWith asthma
heart failure
obesity
hypertension
gptkbp:binds norepinephrine
epinephrine
gptkbp:discoveredBy gptkb:Alfred_G._Gilman
gptkb:Elliott_V._McCarty
gptkbp:encodedBy gptkb:ADRB1_gene
gptkb:ADRB2_gene
gptkb:ADRB3_gene
gptkbp:foundIn heart
lungs
adipose tissue
smooth muscle
gptkbp:function lipolysis
smooth muscle relaxation
bronchodilation
regulation of cardiac output
https://www.w3.org/2000/01/rdf-schema#label beta-adrenergic receptor
gptkbp:inhibitedBy beta blocker
gptkbp:locatedIn gptkb:plasma_membrane
gptkbp:MeSH_ID D001638
gptkbp:OMIM 109690
gptkbp:regulates adenylate cyclase activity
glycogenolysis
intracellular calcium levels
renin secretion
gptkbp:structure 7 transmembrane domains
gptkbp:subclassOf adrenergic receptor
gptkbp:subspecies gptkb:beta-2_adrenergic_receptor
gptkb:beta-3_adrenergic_receptor
beta-1 adrenergic receptor
gptkbp:targetOfDrug beta agonist
beta antagonist
gptkbp:type gptkb:cAMP_pathway
gptkbp:UniProtID P08588
gptkbp:bfsParent gptkb:G_protein-coupled_receptor
gptkb:G_protein-coupled_receptors
gptkbp:bfsLayer 5