|
gptkbp:instanceOf
|
gptkb:cell_membrane
gptkb:G_protein-coupled_receptor
|
|
gptkbp:activatedBy
|
gptkb:catecholamines
|
|
gptkbp:associatedWith
|
asthma
heart failure
obesity
hypertension
|
|
gptkbp:binds
|
norepinephrine
epinephrine
|
|
gptkbp:discoveredBy
|
gptkb:Alfred_G._Gilman
gptkb:Elliott_V._McCarty
|
|
gptkbp:encodedBy
|
gptkb:ADRB1_gene
gptkb:ADRB2_gene
gptkb:ADRB3_gene
|
|
gptkbp:foundIn
|
gptkb:adipose_tissue
heart
lungs
smooth muscle
|
|
gptkbp:function
|
lipolysis
smooth muscle relaxation
bronchodilation
regulation of cardiac output
|
|
gptkbp:inhibitedBy
|
gptkb:beta_blocker
|
|
gptkbp:locatedIn
|
gptkb:plasma_membrane
|
|
gptkbp:MeSH_ID
|
D001638
|
|
gptkbp:OMIM
|
109690
|
|
gptkbp:regulates
|
adenylate cyclase activity
glycogenolysis
intracellular calcium levels
renin secretion
|
|
gptkbp:structure
|
7 transmembrane domains
|
|
gptkbp:subclassOf
|
gptkb:adrenergic_receptor
|
|
gptkbp:subspecies
|
gptkb:beta-2_adrenergic_receptor
gptkb:beta-3_adrenergic_receptor
beta-1 adrenergic receptor
|
|
gptkbp:targetOfDrug
|
beta agonist
beta antagonist
|
|
gptkbp:type
|
gptkb:cAMP_pathway
|
|
gptkbp:UniProtID
|
P08588
|
|
gptkbp:bfsParent
|
gptkb:G_protein-coupled_receptors
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
beta-adrenergic receptor
|