Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alsoKnownAs |
gptkb:KIT
gptkb:CD117 |
| gptkbp:discoveredBy |
gptkb:Tak_W._Mak
|
| gptkbp:encodedBy |
gptkb:KIT_gene
|
| gptkbp:expressedIn |
gptkb:melanocytes
gptkb:germ_cells hematopoietic stem cells |
| gptkbp:function |
gptkb:receptor_tyrosine_kinase
|
| gptkbp:HGNC_ID |
6342
|
| https://www.w3.org/2000/01/rdf-schema#label |
proto-oncogene c-Kit
|
| gptkbp:involvedIn |
cell proliferation
melanogenesis hematopoiesis gametogenesis |
| gptkbp:ligand |
gptkb:stem_cell_factor
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_4
|
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:mutationAssociatedWith |
gptkb:gastrointestinal_stromal_tumor
gptkb:mastocytosis gptkb:acute_myeloid_leukemia piebladism |
| gptkbp:OMIM |
164920
|
| gptkbp:orthologInMouse |
gptkb:Kit
|
| gptkbp:targetOfDrug |
gptkb:dasatinib
gptkb:imatinib gptkb:sunitinib |
| gptkbp:UniProtID |
P10721
|
| gptkbp:bfsParent |
gptkb:c-KIT
|
| gptkbp:bfsLayer |
7
|