protein tyrosine phosphatase family

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:discoveredBy	gptkb:Edwin_G._Krebs gptkb:Edmond_H._Fischer
gptkbp:domain	gptkb:protein_tyrosine_phosphatase_domain
gptkbp:EC_number	3.1.3.48
gptkbp:firstDescribed	1988
gptkbp:foundIn	eukaryotes
gptkbp:function	dephosphorylation of tyrosine residues
gptkbp:GeneOntologyTerm	gptkb:GO:0004725
gptkbp:hasMember	gptkb:PTPN11 gptkb:PTPRM gptkb:PTPN1 gptkb:PTPN2 gptkb:PTPRC gptkb:PTPRD gptkb:PTPRF gptkb:PTPRG gptkb:PTPRT gptkb:PTPRZ1 gptkb:PTPRJ gptkb:PTPRK gptkb:PTPRO gptkb:PTPRQ PTPRN
gptkbp:hasType	non-receptor-type PTP receptor-type PTP
https://www.w3.org/2000/01/rdf-schema#label	protein tyrosine phosphatase family
gptkbp:involvedIn	gptkb:diabetes signal transduction autoimmune diseases immune response oncogenesis
gptkbp:regulates	cell differentiation metabolism cell growth cell signaling cell cycle
gptkbp:relatedTo	protein kinase family
gptkbp:subfamily	gptkb:CDC25_phosphatases gptkb:phosphatase_and_tensin_homolog_(PTEN) classical PTPs dual-specificity PTPs eyes absent (EYA) phosphatases low molecular weight PTPs
gptkbp:UniProtID	gptkb:PTP_family
gptkbp:bfsParent	gptkb:LAR_gene
gptkbp:bfsLayer	6