|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:PTP_delta
gptkb:R-PTP-delta
gptkb:hPTPdelta
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:autism_spectrum_disorder
gptkb:restless_legs_syndrome
|
|
gptkbp:biologicalProcess
|
cell adhesion
protein tyrosine phosphatase activity
axon guidance
synapse formation
|
|
gptkbp:discoveredBy
|
Tonks et al.
|
|
gptkbp:encodes
|
gptkb:receptor-type_tyrosine-protein_phosphatase_delta
|
|
gptkbp:Entrez_Gene_ID
|
5789
ENSG00000153707
|
|
gptkbp:expressedIn
|
gptkb:nervous_system
brain
|
|
gptkbp:firstDescribed
|
1992
|
|
gptkbp:fullName
|
gptkb:protein_tyrosine_phosphatase,_receptor_type_D
|
|
gptkbp:function
|
cell signaling
neuronal development
regulation of cell growth
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GOID
|
GO:0007155
GO:0005001
GO:0007411
|
|
gptkbp:hasParalog
|
gptkb:PTPRF
gptkb:PTPRG
gptkb:PTPRT
|
|
gptkbp:HGNC_ID
|
HGNC:9667
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PTPRD
|
|
gptkbp:interactsWith
|
gptkb:IL1RAPL1
gptkb:Liprin-alpha
gptkb:NGL-3
gptkb:SLITRK1
gptkb:SLITRK2
|
|
gptkbp:length
|
35 exons
|
|
gptkbp:locatedOnChromosome
|
gptkb:9p24.1
gptkb:chromosome_9
|
|
gptkbp:mutationAssociatedWith
|
deletion
missense mutation
nonsense mutation
tumor suppressor loss
|
|
gptkbp:OMIM
|
601598
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Ptprd
|
|
gptkbp:proteinFamily
|
gptkb:protein_tyrosine_phosphatase_family
phosphatase domain
immunoglobulin-like domain
fibronectin type III domain
|
|
gptkbp:regulates
|
subject to epigenetic silencing in cancer
|
|
gptkbp:UniProtID
|
Q16827
|
|
gptkbp:bfsParent
|
gptkb:protein_tyrosine_phosphatases
|
|
gptkbp:bfsLayer
|
6
|