PTPRO

GPTKB entity

Statements (34)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alternativeName GLEPP1
PTP O
PTP-U2
gptkbp:associatedWith chronic lymphocytic leukemia
nephrotic syndrome
gptkbp:domain gptkb:protein_tyrosine_phosphatase_domain
fibronectin type III domain
gptkbp:encodes Receptor-type tyrosine-protein phosphatase O
gptkbp:Entrez_Gene_ID 5799
ENSG00000145041
gptkbp:expressedIn gptkb:cancer
gptkb:kidney
brain
gptkbp:fullName protein tyrosine phosphatase, receptor type O
gptkbp:function cell signaling
protein dephosphorylation
gptkbp:geneType protein-coding
gptkbp:HGNC_ID HGNC:9660
https://www.w3.org/2000/01/rdf-schema#label PTPRO
gptkbp:locatedOnChromosome gptkb:chromosome_12
gptkbp:mutationAssociatedWith glomerular disease
gptkbp:OMIM 601597
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse Ptpro
gptkbp:proteinFamily gptkb:protein_tyrosine_phosphatase_family
gptkbp:regulates glomerular filtration
podocyte structure
gptkbp:subcellularLocation gptkb:cell_membrane
single-pass type I membrane protein
gptkbp:UniProtID Q16827
gptkbp:bfsParent gptkb:PTP_gene_family
gptkb:protein_tyrosine_phosphatase_family
gptkbp:bfsLayer 7