|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:HPTPZ
gptkb:PTP-Zeta
gptkb:R-PTP-zeta
gptkb:RPTP-beta
|
|
gptkbp:alternativeSplicing
|
produces multiple isoforms
|
|
gptkbp:associatedWith
|
gptkb:glioblastoma
schizophrenia
multiple sclerosis
|
|
gptkbp:biologicalProcess
|
signal transduction
nervous system development
cell adhesion
protein tyrosine phosphatase activity
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
extracellular region
|
|
gptkbp:discoveredBy
|
Shintani et al.
|
|
gptkbp:discoveredIn
|
1991
|
|
gptkbp:encodes
|
gptkb:Receptor-type_tyrosine-protein_phosphatase_zeta
|
|
gptkbp:Entrez_Gene_ID
|
5803
ENSG00000185650
|
|
gptkbp:expressedIn
|
brain
central nervous system
|
|
gptkbp:fullName
|
gptkb:Protein_tyrosine_phosphatase_receptor_type_Z1
|
|
gptkbp:function
|
cell signaling
regulation of cell growth
regulation of differentiation
regulation of migration
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GOID
|
GO:0005001
|
|
gptkbp:hasTranscriptVariant
|
3
|
|
gptkbp:HGNC_ID
|
HGNC:9660
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PTPRZ1
|
|
gptkbp:interactsWith
|
gptkb:beta-catenin
gptkb:MAGI-1
gptkb:contactin-1
gptkb:pleiotrophin
gptkb:tenascin-C
|
|
gptkbp:length
|
2316
|
|
gptkbp:locatedOnChromosome
|
7
|
|
gptkbp:location
|
7q31.32
|
|
gptkbp:molecularWeight
|
~250 kDa
|
|
gptkbp:OMIM
|
176891
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Ptprz1
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:UniProtID
|
P23471
|
|
gptkbp:bfsParent
|
gptkb:protein_tyrosine_phosphatases
|
|
gptkbp:bfsLayer
|
6
|