|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
BIA15
CD148
DEP-1
HPTPη
PTP-eta
|
|
gptkbp:associatedWith
|
gptkb:cancer
colorectal cancer
angiogenesis
glioma
|
|
gptkbp:discoveredBy
|
Ostman et al.
|
|
gptkbp:Entrez_Gene_ID
|
5795
ENSG00000149177
|
|
gptkbp:expressedIn
|
hematopoietic cells
endothelial cells
epithelial cells
|
|
gptkbp:firstDescribed
|
1994
|
|
gptkbp:fullName
|
Protein Tyrosine Phosphatase, Receptor Type J
|
|
gptkbp:function
|
regulation of cell differentiation
negative regulation of cell proliferation
regulation of cell growth
protein tyrosine phosphatase activity
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GO_term
|
gptkb:GO:0004713
GO:0005001
|
|
gptkbp:HGNC_ID
|
gptkb:PTPRJ
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PTPRJ
|
|
gptkbp:locatedIn
|
gptkb:plasma_membrane
|
|
gptkbp:locatedOnChromosome
|
gptkb:11p11.2
11
|
|
gptkbp:membrane_protein
|
true
|
|
gptkbp:MIM_number
|
601936
|
|
gptkbp:mutationAssociatedWith
|
tumorigenesis
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Ptprj
|
|
gptkbp:proteinFamily
|
receptor-type protein tyrosine phosphatase
|
|
gptkbp:regulates
|
gptkb:Src_family_kinases
cell migration
cell signaling
EGFR signaling
PDGFR signaling
cell adhesion
VEGFR2 signaling
|
|
gptkbp:transmembraneDomains
|
single-pass
|
|
gptkbp:UniProtID
|
Q12913
|
|
gptkbp:bfsParent
|
gptkb:PTP_gene_family
gptkb:protein_tyrosine_phosphatase_family
|
|
gptkbp:bfsLayer
|
7
|