|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:PTPrho
gptkb:Receptor-type_tyrosine-protein_phosphatase_T
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:glioblastoma
colorectal cancer
|
|
gptkbp:chromosomeArm
|
q
|
|
gptkbp:discoveredBy
|
genomic sequencing
|
|
gptkbp:domain
|
extracellular domain
transmembrane domain
intracellular phosphatase domain
|
|
gptkbp:encodes
|
gptkb:Receptor-type_tyrosine-protein_phosphatase_T
|
|
gptkbp:Entrez_Gene_ID
|
11122
ENSG00000169242
|
|
gptkbp:expressedIn
|
brain
liver
colon
|
|
gptkbp:fullName
|
gptkb:protein_tyrosine_phosphatase,_receptor_type_T
|
|
gptkbp:function
|
signal transduction
regulation of cell differentiation
regulation of cell growth
|
|
gptkbp:gene_structure
|
multiple exons
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GO_term
|
GO:0004725 (protein tyrosine phosphatase activity)
GO:0005886 (plasma membrane)
GO:0007165 (signal transduction)
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
HGNC:9660
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PTPRT
|
|
gptkbp:length
|
1,453 amino acids
|
|
gptkbp:locatedOnChromosome
|
20
20q12-q13.11
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:molecularWeight
|
~163 kDa
|
|
gptkbp:mutationAssociatedWith
|
nonsense
missense
frameshift
tumor suppressor inactivation
|
|
gptkbp:OMIM
|
609889
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Ptprt
|
|
gptkbp:pathway
|
signal transduction
neuronal development
cell adhesion
|
|
gptkbp:proteinFamily
|
gptkb:protein_tyrosine_phosphatase
|
|
gptkbp:subcellularLocation
|
gptkb:plasma_membrane
|
|
gptkbp:UniProtID
|
Q7Z6J6
|
|
gptkbp:bfsParent
|
gptkb:protein_tyrosine_phosphatases
|
|
gptkbp:bfsLayer
|
6
|