Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
dephosphorylation
|
| gptkbp:associatedWith |
gptkb:cancer
|
| gptkbp:biologicalProcess |
protein tyrosine phosphatase activity
|
| gptkbp:discoveredBy |
gptkb:Saccharomyces_cerevisiae
|
| gptkbp:enzymeClassification |
EC 3.1.3.48
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
dephosphorylation of cyclin-dependent kinases
|
| gptkbp:gene |
CDC25
|
| gptkbp:hasMember |
gptkb:CDC25C
CDC25A CDC25B |
| gptkbp:inhibitedBy |
phosphorylation
|
| gptkbp:involves |
DNA damage response
G2/M transition of mitotic cell cycle |
| gptkbp:regulates |
cell cycle progression
|
| gptkbp:relatedTo |
cell proliferation
|
| gptkbp:subcellularLocation |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:target |
checkpoint kinases
|
| gptkbp:bfsParent |
gptkb:14-3-3_proteins
gptkb:PTP_gene_family gptkb:CDK1 gptkb:protein_tyrosine_phosphatase_family |
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
CDC25 phosphatases
|