|
gptkbp:instanceOf
|
antidepressant
selective serotonin reuptake inhibitor
|
|
gptkbp:approvedBy
|
1992
|
|
gptkbp:ATCCode
|
N06AB05
|
|
gptkbp:brand
|
gptkb:Paxil
gptkb:Seroxat
|
|
gptkbp:CASNumber
|
61869-08-7
|
|
gptkbp:chemicalClass
|
gptkb:phenylpiperidine
|
|
gptkbp:contraindication
|
concurrent use with MAO inhibitors
|
|
gptkbp:developedBy
|
GlaxoSmithKline
|
|
gptkbp:drugInteraction
|
gptkb:beer
gptkb:tricyclic_antidepressants
gptkb:warfarin
gptkb:MAO_inhibitors
gptkb:NSAIDs
lithium
antipsychotics
anticonvulsants
other SSRIs
|
|
gptkbp:eliminationHalfLife
|
21 hours
|
|
gptkbp:excretion
|
urine
feces
|
|
gptkbp:genericAvailable
|
yes
|
|
gptkbp:hasMolecularFormula
|
C19H20FNO3
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
paroxetine
|
|
gptkbp:KEGGID
|
D02366
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits reuptake of serotonin
|
|
gptkbp:MedlinePlusID
|
a698032
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:overdoseSymptoms
|
gptkb:arrhythmia
nausea
vomiting
tremor
seizures
drowsiness
|
|
gptkbp:pregnancyCategory
|
D (US)
|
|
gptkbp:pregnancyRisk
|
may cause birth defects
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL418
43815
DB00715
|
|
gptkbp:riskFactor
|
gptkb:serotonin_syndrome
increased suicidal thoughts in young people
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
nausea
weight gain
sweating
insomnia
drowsiness
dry mouth
sexual dysfunction
withdrawal symptoms
|
|
gptkbp:UNII
|
41VRH5220H
|
|
gptkbp:usedFor
|
gptkb:generalized_anxiety_disorder
gptkb:obsessive-compulsive_disorder
gptkb:panic_disorder
gptkb:post-traumatic_stress_disorder
gptkb:social_anxiety_disorder
gptkb:major_depressive_disorder
premenstrual dysphoric disorder
|
|
gptkbp:bfsParent
|
gptkb:CYP2D6
gptkb:CYP3A4
|
|
gptkbp:bfsLayer
|
5
|