|
gptkbp:instanceOf
|
gptkb:medical_condition
|
|
gptkbp:affects
|
central nervous system
autonomic nervous system
neuromuscular system
|
|
gptkbp:alsoKnownAs
|
gptkb:serotonin_toxicity
|
|
gptkbp:causedBy
|
drug interactions
excess serotonergic activity
use of serotonergic drugs
|
|
gptkbp:complication
|
gptkb:death
renal failure
seizures
rhabdomyolysis
|
|
gptkbp:diagnosedBy
|
gptkb:Hunter_Serotonin_Toxicity_Criteria
clinical assessment
|
|
gptkbp:differentialDiagnosis
|
gptkb:anticholinergic_toxicity
malignant hyperthermia
neuroleptic malignant syndrome
|
|
gptkbp:field
|
gptkb:medicine
|
|
gptkbp:firstDescribed
|
1950s
|
|
gptkbp:ICD-10_code
|
T43.2
|
|
gptkbp:MeSH_ID
|
D020528
|
|
gptkbp:prevention
|
avoid drug interactions
careful medication management
|
|
gptkbp:riskFactor
|
gptkb:tricyclic_antidepressants
gptkb:SSRIs
gptkb:MDMA
gptkb:SNRIs
gptkb:linezolid
gptkb:St._John's_Wort
gptkb:tramadol
MAOIs
|
|
gptkbp:symptom
|
confusion
fever
diarrhea
hypertension
tremor
sweating
tachycardia
agitation
myoclonus
muscle rigidity
hyperreflexia
|
|
gptkbp:treatment
|
gptkb:benzodiazepines
gptkb:cyproheptadine
supportive care
discontinuation of serotonergic drugs
|
|
gptkbp:bfsParent
|
gptkb:Ecstasy
gptkb:dextromethorphan
gptkb:Cymbalta
gptkb:Prozac
gptkb:methylene_blue
gptkb:MDMA
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
serotonin syndrome
|