|
gptkbp:instanceOf
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medical condition
|
|
gptkbp:affects
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central nervous system
autonomic nervous system
neuromuscular system
|
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gptkbp:alsoKnownAs
|
gptkb:serotonin_toxicity
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gptkbp:causedBy
|
drug interactions
excess serotonergic activity
use of serotonergic drugs
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gptkbp:complication
|
death
renal failure
seizures
rhabdomyolysis
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gptkbp:diagnosedBy
|
gptkb:Hunter_Serotonin_Toxicity_Criteria
clinical assessment
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gptkbp:differentialDiagnosis
|
gptkb:anticholinergic_toxicity
malignant hyperthermia
neuroleptic malignant syndrome
|
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gptkbp:field
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gptkb:medicine
|
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gptkbp:firstDescribed
|
1950s
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|
https://www.w3.org/2000/01/rdf-schema#label
|
serotonin syndrome
|
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gptkbp:ICD-10_code
|
T43.2
|
|
gptkbp:MeSH_ID
|
D020528
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gptkbp:prevention
|
avoid drug interactions
careful medication management
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gptkbp:riskFactor
|
gptkb:tricyclic_antidepressants
gptkb:SSRIs
gptkb:MDMA
gptkb:SNRIs
gptkb:linezolid
gptkb:St._John's_Wort
gptkb:tramadol
MAOIs
|
|
gptkbp:symptom
|
confusion
fever
diarrhea
hypertension
tremor
sweating
tachycardia
agitation
myoclonus
muscle rigidity
hyperreflexia
|
|
gptkbp:treatment
|
gptkb:benzodiazepines
gptkb:cyproheptadine
supportive care
discontinuation of serotonergic drugs
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gptkbp:bfsParent
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gptkb:Zoloft
gptkb:Zofran
|
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gptkbp:bfsLayer
|
5
|