major depressive disorder

GPTKB entity

Statements (66)
Predicate Object
gptkbp:instanceOf mental disorder
mood disorder
gptkbp:affects gptkb:Animalia
cognition
mood
physical health
gptkbp:alsoKnownAs gptkb:MDD
clinical depression
gptkbp:canBeChronic yes
gptkbp:characterizedBy gptkb:anhedonia
fatigue
sleep disturbances
suicidal thoughts
loss of interest
changes in appetite
feelings of worthlessness
impaired concentration
persistent low mood
gptkbp:complication suicide
substance abuse
impaired social functioning
increased risk of physical illness
gptkbp:diagnosedBy gptkb:DSM-5_criteria
gptkb:ICD-10_criteria
clinical interview
gptkbp:DSM-5_code 296.2
296.3
gptkbp:field clinical psychology
psychiatry
gptkbp:firstDescribed gptkb:Emil_Kraepelin
https://www.w3.org/2000/01/rdf-schema#label major depressive disorder
gptkbp:ICD-10_code gptkb:F32
gptkb:F33
gptkbp:onset typically in adolescence or early adulthood
gptkbp:prevalence more common in women
common worldwide
gptkbp:recurrence yes
gptkbp:riskFactor gptkb:trauma
chronic illness
substance abuse
genetic predisposition
chronic stress
family history of depression
gptkbp:subspecies gptkb:depression
gptkb:melancholic_depression
gptkb:peripartum_depression
gptkb:psychotic_depression
atypical depression
gptkbp:symptom insomnia
difficulty concentrating
depressed mood
feelings of guilt
hypersomnia
loss of pleasure
psychomotor agitation
psychomotor retardation
recurrent thoughts of death
gptkbp:treatment gptkb:psychotherapy
support groups
lifestyle changes
cognitive behavioral therapy
electroconvulsive therapy
antidepressant medication
gptkbp:bfsParent gptkb:depression
gptkb:Brodmann_area_25
gptkbp:bfsLayer 4