Statements (71)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:mental_disorder
gptkb:mood_disorder |
| gptkbp:affects |
gptkb:Animalia
cognition mood physical health |
| gptkbp:alsoKnownAs |
gptkb:MDD
clinical depression |
| gptkbp:canBeChronic |
yes
|
| gptkbp:characterizedBy |
gptkb:anhedonia
fatigue sleep disturbances suicidal thoughts loss of interest changes in appetite feelings of worthlessness impaired concentration persistent low mood |
| gptkbp:complication |
gptkb:substance_abuse
suicide impaired social functioning increased risk of physical illness |
| gptkbp:diagnosedBy |
gptkb:DSM-5_criteria
gptkb:ICD-10_criteria clinical interview |
| gptkbp:DSM-5_code |
296.2
296.3 |
| gptkbp:field |
clinical psychology
psychiatry |
| gptkbp:firstDescribed |
gptkb:Emil_Kraepelin
|
| gptkbp:ICD-10_code |
gptkb:F32
gptkb:F33 |
| gptkbp:onset |
typically in adolescence or early adulthood
|
| gptkbp:prevalence |
more common in women
common worldwide |
| gptkbp:recurrence |
yes
|
| gptkbp:riskFactor |
gptkb:substance_abuse
gptkb:trauma chronic illness genetic predisposition chronic stress family history of depression |
| gptkbp:subspecies |
gptkb:depression
gptkb:melancholic_depression gptkb:peripartum_depression gptkb:psychotic_depression atypical depression |
| gptkbp:symptom |
insomnia
difficulty concentrating depressed mood feelings of guilt hypersomnia loss of pleasure psychomotor agitation psychomotor retardation recurrent thoughts of death |
| gptkbp:treatment |
gptkb:psychotherapy
support groups lifestyle changes cognitive behavioral therapy electroconvulsive therapy antidepressant medication |
| gptkbp:bfsParent |
gptkb:brain-derived_neurotrophic_factor
gptkb:John_Hinckley_Jr. gptkb:Stanley_Center_for_Psychiatric_Research gptkb:D08402 gptkb:Cymbalta gptkb:Prozac gptkb:Transcranial_Magnetic_Stimulation |
| gptkbp:bfsLayer |
6
|
| https://www.w3.org/2000/01/rdf-schema#label |
major depressive disorder
|