neurotrophic receptor tyrosine kinase 2

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein gptkb:gene
gptkbp:alsoKnownAs	gptkb:TrkB gptkb:NTRK2
gptkbp:binds	gptkb:brain-derived_neurotrophic_factor gptkb:neurotrophin-3 gptkb:neurotrophin-4
gptkbp:biologicalProcess	protein kinase activity
gptkbp:cellularComponent	gptkb:plasma_membrane
gptkbp:discoveredBy	L.F. Parada et al.
gptkbp:encodedBy	gptkb:NTRK2_gene
gptkbp:Entrez_Gene_ID	gptkb:ENSG00000148053 4915
gptkbp:expressedIn	brain central nervous system
gptkbp:function	gptkb:receptor_tyrosine_kinase
gptkbp:geneType	protein-coding
gptkbp:HGNC_ID	8032
https://www.w3.org/2000/01/rdf-schema#label	neurotrophic receptor tyrosine kinase 2
gptkbp:involvedIn	gptkb:synaptic_plasticity cell survival neuronal development
gptkbp:locatedOnChromosome	gptkb:chromosome_9
gptkbp:mutationAssociatedWith	gptkb:cancer neurodevelopmental disorders
gptkbp:OMIM	600456
gptkbp:organism	gptkb:Homo_sapiens
gptkbp:orthologInMouse	gptkb:Ntrk2
gptkbp:PDB	gptkb:1HCF
gptkbp:target	gptkb:entrectinib gptkb:larotrectinib
gptkbp:UniProtID	gptkb:Q16620
gptkbp:bfsParent	gptkb:NTRK2
gptkbp:bfsLayer	7