matrix metallopeptidase 7

URI: https://gptkb.org/entity/matrix_metallopeptidase_7
GPTKB entity
Statements (49)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:enzyme
gptkbp:alternativeName gptkb:matrilysin
gptkb:MMP-7
gptkbp:associatedWith gptkb:cancer
colorectal cancer
pancreatic cancer
prostate cancer
gastric cancer
gptkbp:EC_number 3.4.24.23
gptkbp:encodedBy gptkb:MMP7_gene
gptkbp:Entrez_Gene_ID gptkb:ENSG00000149968
4316
gptkbp:expressedIn epithelial cells
gptkbp:function degrades components of the extracellular matrix
involved in tissue remodeling
involved in wound healing
involved in cancer metastasis
gptkbp:gene gptkb:MMP7
gptkbp:GOID gptkb:GO:0005615
GO:0004222
GO:0005578
GO:0006508
GO:0008237
GO:0030198
gptkbp:hasPfam PF00413
gptkbp:hasRefSeqID NP_002414.1
gptkbp:HGNC_ID gptkb:HGNC:7176
https://www.w3.org/2000/01/rdf-schema#label matrix metallopeptidase 7
gptkbp:inhibitedBy tissue inhibitor of metalloproteinases (TIMP)
gptkbp:InterPro IPR001420
gptkbp:KEGGID hsa:4316
gptkbp:locatedOnChromosome chromosome 11q22.2
gptkbp:molecularWeight 28 kDa
gptkbp:OMIM 600305
gptkbp:organism gptkb:Homo_sapiens
gptkbp:PDB 1MMQ
1MMR
2Y6C
gptkbp:Reactome R-HSA-1592389
gptkbp:substrate gptkb:fibronectin
gptkb:elastin
gptkb:casein
gptkb:collagen_IV
gelatin
proteoglycans
gptkbp:UniProtID gptkb:P09237
gptkbp:bfsParent gptkb:MMP7
gptkbp:bfsLayer 7