Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
collagen |
| gptkbp:associatedWith |
gptkb:Alport_syndrome
gptkb:Goodpasture_syndrome |
| gptkbp:component |
extracellular matrix
|
| gptkbp:discoveredIn |
basement membranes
|
| gptkbp:encodedBy |
gptkb:COL4A2_gene
gptkb:COL4A3_gene gptkb:COL4A4_gene gptkb:COL4A5_gene gptkb:COL4A6_gene gptkb:COL4A1_gene |
| gptkbp:features |
interrupted triple helix
|
| gptkbp:form |
network-like structure
heterotrimers |
| gptkbp:foundIn |
basement membrane
|
| gptkbp:function |
structural support
|
| https://www.w3.org/2000/01/rdf-schema#label |
collagen IV
|
| gptkbp:importantFor |
eye structure
kidney filtration barrier vascular integrity |
| gptkbp:molecularWeight |
~400 kDa
|
| gptkbp:mutationAssociatedWith |
hearing loss
hereditary nephritis ocular defects |
| gptkbp:subunit |
gptkb:alpha-1(IV)_chain
gptkb:alpha-2(IV)_chain gptkb:alpha-3(IV)_chain gptkb:alpha-4(IV)_chain gptkb:alpha-5(IV)_chain gptkb:alpha-6(IV)_chain |
| gptkbp:bfsParent |
gptkb:Nidogen_(protein_family)
|
| gptkbp:bfsLayer |
6
|