|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:matrilysin
PUMP-1
|
|
gptkbp:associatedWith
|
gptkb:cancer
inflammatory diseases
fibrosis
|
|
gptkbp:biologicalProcess
|
proteolytic enzyme
cleaves casein, gelatin, fibronectin, and proteoglycans
|
|
gptkbp:discoveredBy
|
Muller et al.
|
|
gptkbp:encodes
|
MMP-7 protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000149968
4316
|
|
gptkbp:expressedIn
|
epithelial cells
|
|
gptkbp:firstDescribed
|
1988
|
|
gptkbp:fullName
|
gptkb:matrix_metallopeptidase_7
|
|
gptkbp:function
|
embryonic development
wound healing
tumor progression
degradation of extracellular matrix
tissue remodeling
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:7176
|
|
gptkbp:length
|
267 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:11q22.2
chromosome 11
|
|
gptkbp:OMIM
|
159406
|
|
gptkbp:orthologInMouse
|
gptkb:Mmp7
|
|
gptkbp:product
|
zinc-dependent endopeptidase
|
|
gptkbp:proteinFamily
|
gptkb:matrix_metalloproteinase_family
|
|
gptkbp:regulates
|
regulated by growth factors
induced by cytokines
|
|
gptkbp:UniProtID
|
gptkb:P09237
|
|
gptkbp:bfsParent
|
gptkb:matrilysin
gptkb:matrix_metallopeptidase_7
gptkb:matrix_metalloproteinase-7
gptkb:MMP-7
gptkb:LEF
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MMP7 gene
|