MMP7 gene

GPTKB entity

Statements (36)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alsoKnownAs gptkb:matrilysin
PUMP-1
gptkbp:associatedWith gptkb:cancer
inflammatory diseases
fibrosis
gptkbp:biologicalProcess proteolytic enzyme
cleaves casein, gelatin, fibronectin, and proteoglycans
gptkbp:discoveredBy Muller et al.
gptkbp:encodes MMP-7 protein
gptkbp:Entrez_Gene_ID gptkb:ENSG00000149968
4316
gptkbp:expressedIn epithelial cells
gptkbp:firstDescribed 1988
gptkbp:fullName gptkb:matrix_metallopeptidase_7
gptkbp:function embryonic development
wound healing
tumor progression
degradation of extracellular matrix
tissue remodeling
gptkbp:geneType protein-coding
gptkbp:hasTranscriptVariant multiple
gptkbp:HGNC_ID gptkb:HGNC:7176
https://www.w3.org/2000/01/rdf-schema#label MMP7 gene
gptkbp:length 267 amino acids
gptkbp:locatedOnChromosome gptkb:11q22.2
chromosome 11
gptkbp:OMIM 159406
gptkbp:orthologInMouse gptkb:Mmp7
gptkbp:product zinc-dependent endopeptidase
gptkbp:proteinFamily gptkb:matrix_metalloproteinase_family
gptkbp:regulates regulated by growth factors
induced by cytokines
gptkbp:UniProtID gptkb:P09237
gptkbp:bfsParent gptkb:LEF
gptkbp:bfsLayer 7