Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alsoKnownAs |
gptkb:MMP-7
|
| gptkbp:associatedWith |
gptkb:cancer
inflammatory diseases |
| gptkbp:discoveredBy |
gptkb:G._Murphy_et_al.
|
| gptkbp:EC_number |
3.4.24.23
|
| gptkbp:encodedBy |
gptkb:MMP7_gene
|
| gptkbp:familyMember |
gptkb:matrix_metalloproteinase
|
| gptkbp:form |
zinc-dependent endopeptidase
|
| gptkbp:foundIn |
humans
other mammals |
| gptkbp:function |
involved in tissue remodeling
involved in wound healing degrades components of extracellular matrix involved in tumor progression |
| https://www.w3.org/2000/01/rdf-schema#label |
matrilysin
|
| gptkbp:inhibitedBy |
gptkb:tissue_inhibitors_of_metalloproteinases_(TIMPs)
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_11q22.3
|
| gptkbp:molecularWeight |
~28 kDa
|
| gptkbp:structure |
lacks hemopexin domain
|
| gptkbp:substrate |
gptkb:fibronectin
gptkb:elastin gptkb:casein gptkb:collagen_IV gelatin |
| gptkbp:bfsParent |
gptkb:MMP7
|
| gptkbp:bfsLayer |
7
|