|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:KOR
KOR-1
OP2
KOR-1 receptor
OPRI
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
addiction
pain perception
opioid response
|
|
gptkbp:discoveredBy
|
Yasuda et al.
|
|
gptkbp:discoveredIn
|
1993
|
|
gptkbp:encodes
|
kappa-type opioid receptor
|
|
gptkbp:Entrez_Gene_ID
|
4985
ENSG00000111275
|
|
gptkbp:expressedIn
|
gptkb:spinal_cord
brain
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:8126
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
OPRK1
|
|
gptkbp:involvedIn
|
stress response
mood regulation
modulation of nociception
|
|
gptkbp:length
|
4 exons
|
|
gptkbp:locatedOnChromosome
|
chromosome 8
|
|
gptkbp:memberOf
|
gptkb:opioid_receptor_family
|
|
gptkbp:mutationAssociatedWith
|
gptkb:depression
alcohol dependence
substance dependence
|
|
gptkbp:OMIM
|
165195
|
|
gptkbp:orthologInMouse
|
Oprk1
|
|
gptkbp:product
|
gptkb:KOR
|
|
gptkbp:proteinFamily
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:receptorFor
|
dynorphins
opioid peptides
|
|
gptkbp:RefSeq
|
NM_000912
|
|
gptkbp:regulates
|
reward pathways
dopamine release
stress-induced analgesia
|
|
gptkbp:relatedTo
|
gptkb:OPRD1
gptkb:OPRM1
OPRL1
|
|
gptkbp:target
|
antagonists
agonists
opioid drugs
|
|
gptkbp:transmembraneDomains
|
7
|
|
gptkbp:UniProtID
|
gptkb:P41145
|
|
gptkbp:bfsParent
|
gptkb:kappa-opioid_receptor
|
|
gptkbp:bfsLayer
|
7
|